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University of Leipzig, Department of General Zoology and Neurobiology
Doctoral Student Position (TV-L 13/2)
Application deadline: not specified

A position for a doctoral student at the University of Leipzig, Department of General Zoology and Neurobiology (Prof. Rudolf Rubsamen) is available in the project
“Development of acoustically evoked and spontaneous pre- and postsynaptic discharge activity in the anteroventral cochlear nucleus (AVCN) and in the medial nucleus of the trapezoid body (MNTB): An electrophysiological study in mice and Mongolian gerbils.”

This is a joint project with Prof. H. v. Gersdorff (Vollum Institute, Portland, Oregon, USA) funded for three years by a DFG Research Grant.
Electrophysiological in vivo and in vitro recordings shall be performed in second order neurons (AVCN) and third order neurons (MNTB) of the ascending auditory system in mice and Mongolian gerbils between postnatal days 6 and 30. This period includes the time before the onset of acoustically evoked signal processing up to (almost) physiological maturity in central auditory signaling. In both target nuclei, the recordings will enable a differentiation between the presynaptic electrical activity and the postsynaptic activity (EPSP and/or action potential) of the respective principal neurons. The data will allow to scrutinize the postnatal development of (i) spontaneous and (ii) stimulus evoked discharge activity, (iii) changes in the reliability of synaptic transmission and (iv) in the synaptic delay in vivo. Mice are chosen because of possibility to use genetically manipulated specimen and gerbils because of their sensitivity to low sound frequencies, which provides the oppor!
tunity for precise analysis of temporal aspects of signal processing (e.g. phase locking).
The Department of General Zoology and Neurobiology (www.uni-leipzig.de/~neuro), located at the Faculty of Biosciences, Pharmacy and Psychology, is embedded in a strong neuroscience research community at the University of Leipzig (www.zv.uni-leipzig.de/forschung/pbf/gehirn-kognition-und-sprache.html). Working facilities are excellent, and PhD students will be affiliated with the DFG Research Training Group InterNeuro (www.uni-leipzig.de/~ineuro/). Funding of the PhD project is for 3 years.

The University of Leipzig is an equal opportunity employer encouraging female scientists and scientists with disabilities to apply.

Please send application papers only in copy without folder or by e-mail. They will be destroyed after a retention period.

Contact address:
Prof. Dr. Rudolf Rubsamen
Department of General Zoology and Neurobiology
Faculty of Biosciences, Pharmacy and Psychology
University of Leipzig
Talstrasse 33, 04103 Leipzig
Phone: +49 (0)341-9736723
Email: rueb@uni-leipzig.de
Web: http://www.uni-leipzig.de/~neuro

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The Children´s Hospital of the Ulm University Hospital is inviting applications for an excellent, highly motivated PhD student in the field of cancer research/apoptosis.

In a multidisciplinary and international research group (group leader: Prof. Simone Fulda), we are studying apoptosis signaling in cancers to identify key molecules that regulate apoptosis in cancer cells.

We aim at translating our knowledge into the development of new cancer therapeutics and novel prognostic biomarkers with a focus on malignant brain tumors (e.g. see FASEB J, 2009, 23:21-33; Cancer Res, 2008, 68:7956-65; Oncogene, 2008, 27:5169-81; Cancer Res, 2008, 68:6271-80; Nat Med, 2002, 8:808-15). Techniques include retroviral gene transfer, siRNA technology, cell & molecular biology, biochemistry, microscopy, primary tumor samples and mouse tumor models.

Benefits:

* The position will be paid according to established scales for PhD students (TV-L/E13, 50%, i.e. roughly 1000 EUR net salary per month).

* Successful applicants have the opportunity to participate in several (inter)national research networks on apoptosis that are coordinated by the project leader, e.g. an EU-funded Marie Curie Research Training Network, a network funded by the German Federal Ministry for Education and Research, and a clinical research group funded by the German Research Foundation.

* Our PhD program – the International Graduate School in Molecular Medicine Ulm – is funded by the Excellence Initiative of the German federal and state governments. This initiative was established in 2005 to grant competitive awards to the best performing German universities.

* The position can be filled immediately for 3 years with the possibility to extend.

Strict Requirements:
* skills in cell and molecular biology
* very good command of English language
* M.Sc. degree (or equivalent) in a highly relevant field (e.g. molecular biology). Candidates with degrees in biotechnology, human or veterinary medicine, bioinformatics, pharmacy and other distantly related areas are not considered, unless they demonstrate experience in apoptosis research.
* Your highest degree must have an average grade of at least 2.0 (in the German grading system) or an equivalent foreign grade (e.g. UK: 80%; France: 17; Italy: 52; India: 78%).
* Candidates from overseas can only be considered if they are able to attend a job interview in Germany. Unfortunately we cannot offer travel refund.

The University of Ulm aims to increase the number of women among the faculty staff and therefore explicitly encourages the application of female scientists.

Application Procedure:
* Your application should at least include your CV, the average grade of your highest degree and 2 references (name, e-mail, phone).
* Please send your application until July 31, 2009 to the assistant of Professor Fulda: nicolas.marschall@uniklinik-ulm.de
* Incomplete applications and applicants not fulfilling the requirements can unfortunately not be considered.
* Late applications are possible, since there are additional positions available regularly.
* Receipt of applications will be confirmed on request only.

If you are interested in cancer research and apoptosis and want to benefit from a cutting-edge research project combined with a structured, interdisciplinary and transeuropean training program, that’s your chance!

Ulm University is an equal opportunity employer and welcomes applications from all qualified individuals.

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Von:

Nicolas Marschall
nicolas.marschall@uniklinik-ulm.de
Uniklinik für Kinder- und Jugendmedizin
Ulm

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A PhD position is available for a research project on the dissection of the neuronal circuits controlling central pain for students with a strong background in Neuroscience or Molecular Biology. Candidates should be highly enthusiastic and motivated to learn new techniques and contribute to new experiments.

Our group is interested in understanding specific neuronal cell populations and their ionic currents in defined neuronal circuits in the mouse nervous system. We use novel genetic methods to manipulate ionic currents in vivo in combination with electrophysiology and behavioral approaches.

The research work will be conducted at the Max Delbrück Center in Berlin, Germany, within the framework of the MolNeuro Research PhD School. The position is available from September 2009

Please send curriculum vitae, cover letter and the name, address and email of two references to Dr. Ines Ibañez-Tallon, Molecular Neurobiology Group, Max-Delbrück-Center, Robert-Rössle-Str. 10, D-13125 Berlin, Germany, ibanezi@mdc.berlin-de.

Ines Ibanez-Tallon
ibanezi@mdc-berlin.de
Max Delbrück Center for Molecular Medicine (MDC)
Berlin, Germany

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