Posts Tagged ‘institute of general botany’

We offer a PhD position that is financed by the DFG (TV-L/2) for 3 years the Institute of General Botany. The focus of this project is on the further functional analyses of a temporal regulated protein disulfide isomerase (PDI) and its role in the circadian system of the green alga Chlamydomonas reinhardtii. Protein disulfide isomerases are known to play important roles in the folding of nascent proteins and in the formation of disulfide bonds. With a combination of heparin affinity chromatography, two-dimensional gel electrophoresis and mass spectrometry, we identified a PDI that is specifically enriched by heparin in samples taken during subjective night. It may play a role in circadian redox signaling pathways and/or act in folding other proteins in a circadian gated way.



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