University of Leipzig, Department of General Zoology and Neurobiology
Doctoral Student Position (TV-L 13/2)
Application deadline: not specified
A position for a doctoral student at the University of Leipzig, Department of General Zoology and Neurobiology (Prof. Rudolf Rubsamen) is available in the project
“Development of acoustically evoked and spontaneous pre- and postsynaptic discharge activity in the anteroventral cochlear nucleus (AVCN) and in the medial nucleus of the trapezoid body (MNTB): An electrophysiological study in mice and Mongolian gerbils.”
This is a joint project with Prof. H. v. Gersdorff (Vollum Institute, Portland, Oregon, USA) funded for three years by a DFG Research Grant.
Electrophysiological in vivo and in vitro recordings shall be performed in second order neurons (AVCN) and third order neurons (MNTB) of the ascending auditory system in mice and Mongolian gerbils between postnatal days 6 and 30. This period includes the time before the onset of acoustically evoked signal processing up to (almost) physiological maturity in central auditory signaling. In both target nuclei, the recordings will enable a differentiation between the presynaptic electrical activity and the postsynaptic activity (EPSP and/or action potential) of the respective principal neurons. The data will allow to scrutinize the postnatal development of (i) spontaneous and (ii) stimulus evoked discharge activity, (iii) changes in the reliability of synaptic transmission and (iv) in the synaptic delay in vivo. Mice are chosen because of possibility to use genetically manipulated specimen and gerbils because of their sensitivity to low sound frequencies, which provides the oppor!
tunity for precise analysis of temporal aspects of signal processing (e.g. phase locking).
The Department of General Zoology and Neurobiology (www.uni-leipzig.de/~neuro), located at the Faculty of Biosciences, Pharmacy and Psychology, is embedded in a strong neuroscience research community at the University of Leipzig (www.zv.uni-leipzig.de/forschung/pbf/gehirn-kognition-und-sprache.html). Working facilities are excellent, and PhD students will be affiliated with the DFG Research Training Group InterNeuro (www.uni-leipzig.de/~ineuro/). Funding of the PhD project is for 3 years.
The University of Leipzig is an equal opportunity employer encouraging female scientists and scientists with disabilities to apply.
Please send application papers only in copy without folder or by e-mail. They will be destroyed after a retention period.
Prof. Dr. Rudolf Rubsamen
Department of General Zoology and Neurobiology
Faculty of Biosciences, Pharmacy and Psychology
University of Leipzig
Talstrasse 33, 04103 Leipzig
Phone: +49 (0)341-9736723